Jacob Michaelson, Ph.D.
Associate Professor, Communication Sciences and Disorders
Associate Professor, Psychiatry
Biography
Research focus
Dr. Jake Michaelson's lab studies the effect of genetic variations on the development of the brain, with specific applications in autism and language impairment.
Courses taught
Selected publications / active grants
- Brueggeman, L., Koomar, T. & Michaelson, J. J. (null). Forecasting autism gene discovery with machine learning and genome-scale data. Cold Spring Harbor Laboratory. DOI: 10.1101/370601.
- Loguercio, S., Overall, R. W., Michaelson, J. J., Wiltshire, T., Pletcher, M. T., Miller, B. H., Walker, J. R., Kempermann, G., Su, A. I. & Beyer, A. (null). Integrative analysis of low- and high-resolution eQTL. PLoS One 5 (11) e13920. PMID: 21085707.
- Vervier, K. & Michaelson, J. J. (null). TiSAn: Estimating Tissue Specific Effects of Coding and Noncoding Variants. Bioinformatics. DOI: 10.1093/bioinformatics/bty301.
- Koomar, T. & Michaelson, J. J. (2020). Genetic Intersections of Language and Neuropsychiatric Conditions. Current Psychiatry Reports 22 (1). DOI: 10.1007/s11920-019-1123-z.
- Feliciano, P., Zhou, X., Astrovskaya, I., Turner, T. N., Wang, T., Brueggeman, L., Barnard, R., Hsieh, A., Snyder, L. G., Muzny, D. M., Sabo, A., Gibbs, R. A., Eichler, E. E., O’Roak, B. J., Michaelson, J. J., Volfovsky, N., Shen, Y. & Chung, W. K. (2019). Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes. npj Genomic Medicine 4 (1). DOI: 10.1038/s41525-019-0093-8.
- Dogan, M. V., Grumbach, I. M., Michaelson, J. J. & Philibert, R. A. (2018). Integrated genetic and epigenetic prediction of coronary heart disease in the Framingham Heart Study. PloS one 13 (1) e0190549. PMID: 29293675. DOI: 10.1371/journal.pone.0190549.
- Feliciano, P., Daniels, A. M., Snyder, L. G., Beaumont, A., Camba, A., Esler, A., Gulsrud, A. G., Mason, A., Nicholson, A., Paolicelli, A. M., McKenzie, A. P., Rachubinski, A. L., Stephens, A. N., Simon, A. R., Gutierrez, A., Stedman, A., Shocklee, A. D., Swanson, A., Finucane, B., Hilscher, B. A., Hauf, B., O'Roak, B. J., McKenna, B., Robertson, B. E., Rodriguez, B., Vernoia, B. M., Van Metre, Bonnie, Bradley, C., Cohen, C., Erickson, C. A., Harkins, C., Hayes, C., Lord, C., Martin, C. L., Ortiz, C., Ochoa-Lubinoff, C., Peura, C., Rice, C. E., Rosenberg, C. R., Smith, C. J., Thomas, C., Taylor, C. M., Casey, L., Walston, White Corrie H., Amaral, D. G., Coury, D. L., Sarver, D. E., Istephanous, D., Li, D., Dzung Cong Nugyen, Fox, E. A., Butter, E. M., Berry-Kravis, E., Courchesne, E., Fombonne, E. J., Hofammann, E., Lamarche, E., Wodka, E. L., Matthews, E. T., O'Connor, E., Palen, E., Gwynette, M. F., Miller, F., Dichter, G. S., Marzano, G., Stein, G., Hutter, H., Kaplan, H. E., Li, H., Lechniak, H., Schneider, H. L., Zaydens, H., Arriaga, I., Gerdts, J. A., Cubells, J. F., Cordova, J. M., Gunderson, J., Lillard, J., Manoharan, J., McCracken, J. T., Michaelson, J. J., Neely, J., Orobio, J., Pandey, J., Piven, J., Scherr, J., Sutcliffe, J. S., Tjernagel, J., Wallace, J., Callahan, K., Dent, K., Schweers, K. A., Hamer, K. E., Law, J. K., Lowe, K., O'Brien, K., Smith, K., Pawlowski, K. G., Pierce, K. L., Roeder, K., Abbeduto, L. J., Berry, L. N., Cartner, L. A., Coppola, L. A., Carpenter, L., Cordeiro, L., DeMarco, L., Grosvenor, L. P., Higgins, L., Huang-Storms, L. Y., Hosmer-Quint, L., Herbert, L. M., Kasparson, L., Prock, L. M., Pacheco, L. D., Raymond, L., Simon, L., Soorya, L. V., Wasserburg, L., Lazar, M., Alessandri, M., Brown, M., Currin, M. H., Heyman, M., Hale, M. N., Jones, M., Jordy, M., Morrier, M. J., Sahin, M., Siegel, M. S., Verdi, M., Parlade, M. V., Yinger, M., Bardett, N., Hanna, N., Harris, N., Pottschmidt, N., Russo-Ponsaran, N., Takahashi, N., Ousley, O. Y., Juarez, A. P., Manning, P., Annett, R. D., Bernier, R. A., Clark, R. D., Landa, R. J., Goin-Kochel, R. P., Remington, R., Schultz, R. T., Brewster, S. J., Booker, S., Carpenter, S., Eldred, S., Francis, S., Friedman, S. L., Homer, S., Hepburn, S., Jacob, S., Kanne, S., Lee, S. J., Mastel, S. A., Plate, S., Qiu, S., Sandhu, S., Thompson, S., White, S., Myers, V. J., Singh, V., Yang, W. S., Warren, Z., Amatya, A., Ace, A. J., Chatha, A. S., Lash, A. E., Negron, B., Rigby, C., Ridenour, C., Stock, C. M., Schmidt, D., Fisk, I., Acampado, J., Nestle, J. L., Nestle, J. A., Layman, K., Butler, M. E., Kent, M., Mallardi, M. D., Carriero, N., Lawson, N., Volfovsky, N., Edgar, R., Marini, R., Rana, R., Ganesan, S., Shah, S., Ramsey, T., Chin, W., Jensen, W., Krentz, A. D., Gruber, A. J., Sabo, A., Salomatov, A., Eng, C., Muzny, D., Astrovskaya, I., Gibbs, R. A., Han, X., Shen, Y., Reichardt, L. F. & Chung, W. K. (2018). SPARK: A US Cohort of 50,000 Families to Accelerate Autism Research. (Vols. 97). (3), pp. 488-493. NEURON. DOI: 10.1016/j.neuron.2018.01.015.
- McKenna, B., Koomar, T., Vervier, K., Kremsreiter, J. & Michaelson, J. J. (2018). Whole-genome sequencing in a family with twin boys with autism and intellectual disability suggests multimodal polygenic risk. COLD SPRING HARBOR MOLECULAR CASE STUDIES 4 (6). DOI: 10.1101/mcs.a003285.
- Lutter, M., Bahl, E., Hannah, C., Hofammann, D., Acevedo, S., Cui, H., McAdams, C. J. & Michaelson, J. J. (2017). Novel and ultra-rare damaging variants in neuropeptide signaling are associated with disordered eating behaviors. PLoS One 12 (8) e0181556.
- Vervier, K. & Michaelson, J. J. (2017). TiSAn: Estimating tissue-specific effects of genetic variants.
Research areas
- Speech-Language Pathology